Yuno Gasai is obsessively in love with Yukiteru (Yandere) as one can safely guess from just the simple name of her future diary. Yukiteru's condition and actions are recorded every ten minutes in her "Yukiteru" diary, it also provides small commentary made by Yuno in some of the entries. Its most obvious weakness is that it does not show Yuno's future at all—her condition, situation, or surroundings—unless it somehow involves Yuki. Working with Yukiteru's "Random Diary" diary, however, covers both of their diaries' individual flaws; as it has been said the two make for a perfect combo. Smart, beautiful and diligent—those who don't truly know Gasai Yuno would simply see the model student role she plays while at school. She is secretly obsessed with Yukiteru and would do anything within her power to assist him. She can be quite clingy and is highly fond of stalking him. When obstacles arise that either endangers Yukki's life or threatens their relationship, her thoughts turn murderous and she lets nothing get in the way of her path. Yuno is also able to quickly analyze and adapt to unexpected situations that may arise, and she puts thoughts into action without hesitation, performing what needs to be done without ever losing her nerves. These traits make her one of the strongest players in Deus's game, despite having one of the weakest diaries for providing self survival aid. And while Yukiteru is credited for triggering the greatest shift in future occurrences, Yuno is the one who has created the largest influence in those events. Yuno tends to carry around a box cutter with her at all times, though she will make use of other weaponry such as kitchen knives, hatchets, etc, when required. She is named after Juno (pronounced yu-no in Latin), the Roman goddess of Motherhood and Femininity.

Holo is a wolf harvest deity originally from a land in the north known as Yoitsu. She made a promise with men from a town called Pasloe where she would ensure the town would have good wheat harvests year after year. However, as time went on, the townspeople slowly started to forsake Holo and did not rely on her as they once did. As such, Holo escapes from town in Lawrence's wagon and started traveling with him to see how much the world has changed since she has been in Pasloe. Holo has chosen the form of a girl younger than Lawrence, though she still retains her large white-tipped wolf tail, and ears. Her true form is that of a very large wolf which many people revered and feared. She refers to herself as the "Wise Wolf of Yoitsu" (ヨイツの賢狼). She is typically very haughty and self-sufficient, though due to her isolation for hundreds of years in Pasloe, she gradually feels very lonely, and sometimes shows a more fragile side of herself. She relies on Lawrence for company as she fears loneliness, which is something that Lawrence is very aware of and tries to comfort her in his own way. Holo is also very aware of the different time spans that she and Lawrence have, as a human lifespan is like a blink of an eye for her kind. Holo is quite scared of that fact, but hides it with jokes. She has a peculiar way of speaking, modeled after that of the oiran high-class courtesans. She is fond of delicious food and alcohol, but especially loves apples. She takes pride in her tail and takes special care of it, constantly combing and maintaining it.